Millions of Americans suffer from chronic illnesses many of those with painful side effects. Drugs that are prescribed to patients can compound this with their side effects to the body. Many seek a treatment option that is natural. It is important to know your illness and all your treatment options. Below you will see studies on cannabis as a treatment option for several illnesses as well as cannabinoid deficiency as a cause. Please feel free to share the truth with not only your friends but your doctor as well. Many are not trained in the science of cannabis and do not realize what studies have already been conducted. ~ Cherry Girl
Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
Migraine has numerous relationships to endocannabinoid function. Anandamide (AEA) potentiates 5-HT1A and inhibits 5-HT2A receptors supporting therapeutic efficacy in acute and preventive migraine treatment. Cannabinoids also demonstrate dopamine-blocking and anti-inflammatory effects. AEA is tonically active in the periaqueductal gray matter, a migraine generator. THC modulates glutamatergic neurotransmission via NMDA receptors. Fibromyalgia is now conceived as a central sensitization state with secondary hyperalgesia. Cannabinoids have similarly demonstrated the ability to block spinal, peripheral and gastrointestinal mechanisms that promote pain in headache, fibromyalgia, IBS and related disorders. The past and potential clinical utility of cannabis-based medicines in their treatment is discussed, as are further suggestions for experimental investigation of CECD via CSF examination and neuro-imaging.
Migraine, fibromyalgia, IBS and related conditions display common clinical, biochemical and pathophysiological patterns that suggest an underlying clinical endocannabinoid deficiency that may be suitably treated with cannabinoid medicines.
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- The Human Body and Cannabis: Understanding Our Endocannabinoid System (cherrygurl28.wordpress.com)
- A Natural Choice For Pain Management (cherrygurl28.com)